Hepatitis A virus causes an infection
of liver, with high prevalence rate and affects all age groups. The hepatitis A virus
(HAV) is transmitted through ingestion of contaminated food and water or
through direct contact with an infectious person.
Disparate hepatitis B and C, hepatitis A contagion
does not cause chronic liver disease and is rarely deadly, but it can cause person
weak and infirm and severe or sudden hepatitis (acute liver failure) which is
often deadly.
Hepatitis A is an acute infection with generalized
symptoms accompanied by jaundice and it represents mainly a disease of the
paediatric population. In children, the diseases with Hepatitis A virus (HAV) is generally have no symptoms while in
case of non-immune adolescents and adults may result in acute clinical disease
like fulminant hepatic failure (FHF). Most children (90%) have been infected
with the hepatitis A virus before the age of 10 years; those infected in
childhood do not experience any noticeable symptoms.
HAV is not enveloped and contains a single-stranded
RNA packaged in a protein shell. There is only one serotype found in this, the region that codes for the HAV capsid is highly
conserved clusters of rare codons that restrict antigenic variability. Naturally
the humans and vertebrates are hosts. Transmission routes are faecal-oral and
blood.
HAV and hepatitis E virus (HEV) have an indistinguishable
clinical presentation and the same mode of transmission.
Investigations (e.g., serum acetaminophen) may be
necessary, depending on the findings from the history and clinical examination.
Molecular diagnostic techniques performed on blood and faeces for HAV RNA are
purely research tools at present.
Hepatitis A treatment usually focuses on keeping
comfortable and controlling signs and symptoms.
You may need to:
Rest. Many people with hepatitis A infection feel tired
and sick and have less energy.
Avoid alcohol and use
medications with care.
Your liver may have difficulty processing medications and alcohol. One should
not drink alcohol during medication. It can cause more liver damage.
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